发明名称 COMPOUNDS AND COMPOSITIONS FOR STABILISATION OF HYPOXIA INDUCED FACTOR-2 ALPHA AS METHOD OF CANCER MEDICAL TREATMENT
摘要 FIELD: bioengineering.SUBSTANCE: invention relates to the use of the compound having formulato stabilise a hypoxia induced factor-2 alpha (HIF-2α), for the reduced regulation of phosphoglycerate kinase (PGK) in a cell, and for the increased regulation of the release from the cell of a dissoluble receptor-1 of a vascular endothelial growth factor (sVEGF-1).EFFECT: higher efficiency of the compositions use.13 cl, 15 dwg, 1 tbl, 5 ex
申请公布号 RU2602498(C2) 申请公布日期 2016.11.20
申请号 RU20130156980 申请日期 2012.06.05
申请人 AKEBIA THERAPEUTICS INC. 发明人 SHALVITZ Robert;MARSH Klej;RODA Dzhuli;JUBENK Timoti
分类号 C07D213/16;A61K31/4412;A61P35/00 主分类号 C07D213/16
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