发明名称 |
Process for preparing 3,4-dihydro-2(1H)-quinazolinone derivatives |
摘要 |
3,4-Dihydro-2(1H)-quinazolinones and quniazolinethiones such as 1-cyclopropylmethyl-4-phenyl-6-methoxy-3,4-dihydro-2(1H)-quinazolinone and its thione derivative, are prepared in high yield with high purity by heating the corresponding arylurea or thiourea such as N-cyclopropylmethyl-N-(p-methoxyphenyl) urea or its thiourea derivative, with the corresponding aldehyde such as benzaldehyde in the presence of hydrobromic acid in an inert solvent.
|
申请公布号 |
US4202974(A) |
申请公布日期 |
1980.05.13 |
申请号 |
US19760731574 |
申请日期 |
1976.10.12 |
申请人 |
SUMITOMO CHEMICAL CO LTD |
发明人 |
KATAYAMA, SHIGENARI;KOSHIBA, MASAO;YAMAMOTO, HISAO;YAMAMOTO, MICHIHIRO |
分类号 |
C07D239/78;C07D239/82;C07D409/06;C07D491/056;(IPC1-7):A61K31/50;C07D491/04 |
主分类号 |
C07D239/78 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|