发明名称 |
COMPRESSA DI TEOFILLINA A RILASCIO RALLENTATO CON VOLUME RIDOTTO |
摘要 |
Non-disintegrating tablets containing at least 95% by weight theophylline having a pair of opposing substantially planar surfaces and a very thin cross-section (i.e. 2.03-3.05 mm) have a high bioavailability on ingestion and a relatively steady release rate permitting a 12 hr. dosing interval for maintenance of non-toxic therapeutic blood theophylline concentrations. Excipients or tableting aids are not required, but trace amounts of a tableting lubricant are preferably included to facilitate continuous large scale production. |
申请公布号 |
IT8148406(D0) |
申请公布日期 |
1981.05.06 |
申请号 |
IT19810048406 |
申请日期 |
1981.05.06 |
申请人 |
BRISTOL-MYERS COMPANY |
发明人 |
STEPHEN T.DAVID;DANA BROOKE;CLAUDE E. GALLIAN |
分类号 |
A61K9/20;A61K9/22;A61K31/52;A61K47/12;A61P11/08;(IPC1-7):A61K/ |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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