Analyte sensors comprising high-boiling point solvents

摘要

Generally, embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have improved uniformity of distribution of the sensing layer by inclusion of a high-boiling point solvent, where the sensing layer is disposed proximate to a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

主权项

1. An electrode structure, comprising
a conductive material; and an enzyme formulation disposed on a surface of the conductive material, wherein the enzyme formulation comprises polymer, enzyme, and a high-boiling point solvent comprising ethylene glycol at a concentration of 0.5% to 5% (w/v) of the total formulation of the enzyme formulation.