摘要 |
A process for stabilizing vitamin D by the preparation of an inclusion complex of vitamin D with a cyclodextrin, which comprises forming a homogeneous solution from the vitamin D to be complexed and the cyclodextrin in aqueous ethanol at an elevated temperature, and separating the desired inclusion complex from the solution by cooling and/or by evaporation of solvent. The aqueous ethanol has an ethanol content (58% to 65% by volume) such that both vitamin D and the cyclodextrin are soluble. They can be formulated into pharmaceutical compositions, fodder premixes or fodders in conventional manner. |