| 摘要 |
A compound of the general formula: <CHEM> wherein m is an integer of 10 to 21; R1 is lower alkyl having 1 to 4 carbon atoms; B is a -CH2- or -CO- group, when B is -CH2-, R2 is hydrogen, lower alkyl having 1 to 4 carbon atoms or lower acyl having 1 to 8 carbon atoms, and when B is -CO-, R2 is hydrogen or lower alkyl having 1 to 4 carbon atoms, has pharmaceutical activities such as hypotensive, tissue metabolism stimulating, immunoregulatory, lysosomal membrane stablizing and SRS-A production inhibitory activities and is useful as a heart failure remedy, cerebral circulation disturbance remedy, immunoregulator and antiallergic drug. A compound of the general formula: <CHEM> [wherein each R3 is lower alkyl having 1 to 4 carbon atoms or lower alkoxy having 1 to 4 carbon atoms, or two R3's taken together represent -CH=CH-CH=CH-; n is 0 or an integer of 1 to 20 and when n is 1 to 20, A is -CH2-, -@@- or -CO- and Z is CH2OH, acyloxymethyl having 2 to 11 carbon atoms, esterified or unesterified carboxyl having 1 to 5 carbon atoms, lower alkoxymethyl having 2 to 5 carbon atoms, |
