发明名称 |
FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX. |
摘要 |
The present invention is directed to certain fused pyrimidines having a homo or hetero cyclopentyl, cyclohexyl or cycloheptyl ring as the pyrimidine fusion partner; having an amino benzyl or substituted amino benzyl group at the 4 position of the pyrimidine ring; and a 5:6 heterobicyclo ring with at least one N, O or S at the 2 position of the pyrimidine ring. These compounds are useful for treatment of cancer by inhibition of the p97 complex. |
申请公布号 |
MX2016009465(A) |
申请公布日期 |
2016.12.02 |
申请号 |
MX20160009465 |
申请日期 |
2015.01.19 |
申请人 |
CLEAVE BIOSCIENCES, INC. |
发明人 |
Han-Jie ZHOU;David WUSTROW |
分类号 |
C07D403/04;A61K31/517;A61K31/519;C07D471/04;C07D491/048;C07D491/052 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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