Anti-human papillomavirus monoclonal antibody, hybridoma producing the same and process for preparing the same.

摘要

An anti-human papillomavirus (HPV) monoclonal antibody reactive with various types of HPVs, which is produced by a hybridoma comprising a fused cell of a mouse spleen cell from a mouse immunized with an alkali-treated HPV type 1 (HPV-1) and a mouse myeloma cell, and which is reactive with polypeptides of about 57 kilodaltons, about 160 kilodaltons and about 230 kilodaltons of HPV-1, and a process for preparing the same. The monoclonal antibody of the invention is reactive with various types of HPV and useful for diagnosis of various types of HPV infection (primary diagnosis).