发明名称 |
Cyclopropyl derivative lipoxygenase inhibitors. |
摘要 |
<p>Certain carbocyclic aryl- and heterocyclic aryl- substituted cyclopropyl N-hydroxyureas, N-hydroxy-carboxamides, and N-acyl-N-hydroxyamines inhibit 5- and/or 12-lipoxygenase and are useful in the treatment of inflammatory disease states.</p> |
申请公布号 |
EP0436199(A1) |
申请公布日期 |
1991.07.10 |
申请号 |
EP19900125065 |
申请日期 |
1990.12.21 |
申请人 |
ABBOTT LABORATORIES |
发明人 |
BROOKS, DEE W.;HORROM, BRUCE W.;RODRIQUES, KAREN E.;MAZDIYASNI |
分类号 |
A61K31/16;A61K31/17;A61K31/335;A61K31/357;A61K31/38;A61K31/381;A61K31/40;A61K31/403;A61K31/404;A61K31/425;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4412;A61K31/4418;A61K31/443;A61K31/445;A61K31/47;A61K31/495;A61K31/535;A61K31/5375;A61K31/54;A61P29/00;C07C259/08;A61P43/00;C07C239/08;C07C259/06;C07C275/64;C07D207/32;C07D207/335;C07D209/14;C07D213/30;C07D213/40;C07D213/42;C07D213/61;C07D213/64;C07D213/643;C07D213/65;C07D213/68;C07D215/12;C07D239/26;C07D277/28;C07D277/34;C07D277/64;C07D295/20;C07D307/52;C07D307/56;C07D307/58;C07D307/81;C07D307/83;C07D317/58;C07D319/18;C07D333/16;C07D333/20;C07D333/28;C07D333/32;C07D333/56;C07D333/58;C07D333/64;C07D405/04;C07D409/04 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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