发明名称 NOUVEAUX SUBSTRATS PEPTIDIQUES, PROCEDE DE PREPARATION ET UTILISATION DANS LA DETERMINATION DE LA PROTEINE C.
摘要 Peptide compounds, as novel industrial products, chosen from the series consisting of (i) tripeptides having the formula: Y-A1-A2-A3-R in which Y represents H or a suitable group blocking the N-terminated end, A1 represents an amino-acid group chosen from the series consisting of the groups (2-oxo-thiazolidin-4-yl)carbonyl (THC), (2-oxo-tetrahydro-1,3-thiazin-5-yl)carbonyl (TZC), thiazolidine-4-carbonyl (ATC) and tetrahydro-1,3-thiazin-5-yl)carbonyl (AZC), A2 represents an amino-acid group chosen from the series comprising the groups Pro, 3Hyp and 4Hyp where the 3Hyp and 4Hyp OH lateral group is capable of being protected by a protecting ether or ester group, A3 represents an amino-acid group chosen from the series comprising the groups Arg and Lys and R represents a labelling means; and (ii) their addition salts. These novel compounds are useful as substrates for C protein determination.
申请公布号 FR2658520(A1) 申请公布日期 1991.08.23
申请号 FR19900001966 申请日期 1990.02.19
申请人 SERBIO 发明人 QUENTIN GERARD;MARTINOLI JEAN-LUC
分类号 C07K5/08;C07K5/097;C12Q1/37;C12Q1/56;(IPC1-7):C07K5/08;G01N33/68 主分类号 C07K5/08
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