发明名称 |
EXPRESSED CHEMOKINES, THEIR PRODUCTION AND USES |
摘要 |
The present invention provides nucleotide and amino acid sequences that identify and encode novel expressed chemokines (ECs) from liver and pituitary gland tissues. The present invention also provides for antisense molecules to the nucleotide sequences which encode ECs, expression vectors for the production of purified ECs, antibodies capable of binding specifically to ECs, hybridization probes or oligonucleotides for the detection of EC-encoding nucleotide sequences, genetically engineered host cells for the expression of ECs, diagnostic tests for inflammation or disease based on EC-encoding nucleic acid molecules or antibodies capable of binding specifically to ECs, pharmaceutical compositions to treat inflammation or disease based on ECencoding nucleic acid molecules or antibodies capable of binding specifically to ECs.
|
申请公布号 |
CA2206113(A1) |
申请公布日期 |
1996.06.06 |
申请号 |
CA19952206113 |
申请日期 |
1995.11.29 |
申请人 |
INCYTE PHARMACEUTICALS, INC.;INCYTE PHARMACEUTICALS, INC. |
发明人 |
NEOTE, KULDEEP SINGH;WILDE, CRAIG G.;BANDMAN, OLGA;SEILHAMER, JEFFREY J.;HAWKINS, PHILLIP R. |
分类号 |
G01N33/566;C07K14/52;C07K14/715;C07K16/24;C12N1/21;C12N5/10;C12N15/09;C12N15/19;C12P21/02;C12Q1/68;(IPC1-7):C12N15/19 |
主分类号 |
G01N33/566 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|