发明名称 |
Vectors Conditionally Expressing Protein |
摘要 |
This invention relates to the field of therapeutics. Disclosed are methods of generating conditionally expressing erythropoietin under the control of an ecdysone receptor-based gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. The methods of the invention cause an in vivo increase in the expression of erythropoietin and an increase in the hematocrit or volume percentage of red blood cells in blood after administration of the ligand. |
申请公布号 |
US2016317678(A1) |
申请公布日期 |
2016.11.03 |
申请号 |
US201615151947 |
申请日期 |
2016.05.11 |
申请人 |
Intrexon Corporation |
发明人 |
ROETH Jeremiah F.;Reed Charles C.;Cuthbertson Brandon;Chada Sunil;Fogler William E.;Khazi Fayaz |
分类号 |
A61K48/00;C12N15/86;A61K38/18;C12N15/85;A61K38/20;A61K38/21 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Blacksburg VA US |