Method of making ketoisophorone via oxidation of isophorone with tert-butyl hydroperoxide

摘要

A method of manufacturing 2,6,6-trimethyl-2-cyclohexen-1,4-dione (ketoisophorone) from 3,5,5-trimethyl-2-cyclohexenone (alpha-isophorone). The alpha-isophorone is reacted with hydroperoxide in a solvent, and in the presence of a metal catalyst. The reaction converts the alpha-isophorone directly to ketoisophorone without the intermediate isomerization of alpha-isophorone to beta-isophorone (3,5,5-trimethyl-3-cyclohexenone).