Menetelmä terapeuttisesti käyttökelpoisen (S)-1-(3-dimetyyliaminopropyyli)-1-(4'-fluorifenyyli)-1,3-dihydrobentsofuraani-5-karbonitriilin valmistamiseksi

摘要

The novel (+)-enantiomer of 1-(3-dimethylaminopropyl)-1-(4 min -fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile as well as acid addition salts thereof are described as valuable antidepressants, geriatrics or in the treatment of obesity and alcoholism. Novel intermediates and a method for the preparation of the (+)-enentiomer as well as the racemic mixture are described.