发明名称 |
Novel intermediates and process for the manufacturNovel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and relatede of camptothecin derivatives (CPT-11) and related compounds. compounds. |
摘要 |
PCT No. PCT/US96/04163 Sec. 371 Date Oct. 2, 1997 Sec. 102(e) Date Oct. 2, 1997 PCT Filed Apr. 1, 1996 PCT Pub. No. WO96/31513 PCT Pub. Date Oct. 10, 1996This invention relates to intermediates and processes for the synthesis of camtothecin derivatives, such as irinotecan. Related procedures and compounds are disclosed, such as a method of making mappicine. |
申请公布号 |
ZA9602747(B) |
申请公布日期 |
1998.04.06 |
申请号 |
ZA19960002747 |
申请日期 |
1996.04.04 |
申请人 |
PHARMACIA & UPJOHN COMPANY PHARMACIA & UPJOHN COMPANY |
发明人 |
KEVIN E. HENEGAR KEVIN E. HENEGAR;JOHN C. SIH JOHN C. SIH |
分类号 |
C07D491/147;A61K31/435;A61K31/436;A61K31/4738;A61P35/00;C07C251/26;C07C271/44;C07D213/30;C07D213/61;C07D213/64;C07D213/643;C07D213/79;C07D405/04;C07D471/04;C07D471/14;C07D491/04;C07D491/052;C07D491/14;C07D491/22 |
主分类号 |
C07D491/147 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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