发明名称 |
Stabilization of FSH |
摘要 |
The present invention pertains in general to the field of stabilization of FSH formulations, in particular liquid FSH formulations. The stabilization is achieved by the addition of salts comprising pharmaceutically acceptable alkali metal cations, in preferred embodiments by the addition of pharmaceutically acceptable salts, i.e. sodium salts or potassium salts. |
申请公布号 |
US9463221(B2) |
申请公布日期 |
2016.10.11 |
申请号 |
US201514631382 |
申请日期 |
2015.02.25 |
申请人 |
Ferring B.V. |
发明人 |
Sjogren Helen Ulrika;Bagger Heidi Louise |
分类号 |
C07K1/00;C07K14/00;C07K16/00;C07K17/00;A61K38/24;A61K9/00;A61K47/02;A61K47/12;C07K14/59;A61K47/10 |
主分类号 |
C07K1/00 |
代理机构 |
Fish & Richardson P.C. |
代理人 |
Fish & Richardson P.C. |
主权项 |
1. A liquid formulation comprising:
follicle stimulating hormone (FSH); and sodium sulfate in an amount that stabilizes the FSH. |
地址 |
Hoofddorp NL |