摘要 |
PCT No. PCT/JP94/01900 Sec. 371 Date Jan. 28, 1997 Sec. 102(e) Date Jan. 28, 1997 PCT Filed Nov. 10, 1994 PCT Pub. No. WO96/04279 PCT Pub. Date Feb. 15, 1996Specified imidazoquinoline derivatives represented by the formula (I): <IMAGE> (I) where Q represents an optionally substituted phenyl, pyridyl or furyl group; Y represents either a hydrogen atom or, when taken together with Z, an oxygen atom and a methylene group; Z represents a hydrogen atom, a hydroxymethyl group, a carboxymethyl group, a 2-oxo-1-pyrrolidinyl group or the following formula (III):-A-R2(III)(where A represents an oxygen atom, a sulfur atom or the group -NH-); or salts of such derivatives inhibit the increase of eosinophils and are useful as agents for preventing and/or treating diseases that manifest the increase of eosinophils.
|