| 发明名称 |
Method and Apparatus for In Vitro Kidney Organogenesis |
| 摘要 |
The invention provides for a device, system, and methods for using the same with kidney progenitor cells, specifically ureteric bud (UB) cells, metanephric mesenchymal (MM) cells, and the stromal cell (SC) subpopulation of the metanephric mesenchyme, to generate an embryonic kidney organoid that can be implanted into a mammalian subject to create a living, functional kidney. |
| 申请公布号 |
US2016361466(A1) |
申请公布日期 |
2016.12.15 |
| 申请号 |
US201515121551 |
申请日期 |
2015.02.06 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ;U.S. DEPARTMENT OF VETERANS AFFAIRS |
发明人 |
Yanagawa Norimoto;Nishikawa Masaki;Hamon Morgan;Hauser Peter Viktor |
| 分类号 |
A61L27/36;C12N5/071;C12M3/06;C12M3/00;C12M1/00 |
主分类号 |
A61L27/36 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A kidney mold device for generating an embryonic kidney organoid, the kidney mold device comprising:
a ureteric bud (UB) cell chamber; and a metanephric mesenchymal (MM) cell chamber wherein the MM cell chamber is fluidly connected to the UB cell chamber. |
| 地址 |
Oakland CA US |
