发明名称 Selective and non-invasive visualization or treatment of vasculature
摘要 Disclosed are methods and materials for visualizing or treating vasculature. The methods and materials in this invention relate to selective and non-invasive visualization, or treatment such as chemical occlusion, of vasculature in the mammalian eye. The methods utilize fluorescent dyes and tissue-reactive substances encapsulated within heat-sensitive liposomes which are subsequently heated to release the contents thereof at a pre-determined anatomical locus. The methods of this invention further utilize tissue-reactive agents which, when activated, are effective to cause localized tissue damage and occlusion of blood vessels and/or blood sinuses. The materials of this invention relate to diagnostic reagents and kits for visualizing or treating a mammalian blood vessel or sinus.
申请公布号 US6440950(B1) 申请公布日期 2002.08.27
申请号 US20000676832 申请日期 2000.09.29
申请人 THE JOHNS HOPKINS UNIVERSITY 发明人 ZEIMER RAN
分类号 A61K9/127;A61K41/00;A61K45/06;A61K49/00;A61P41/00;(IPC1-7):A61K31/695;A61K31/685;A61K31/675 主分类号 A61K9/127
代理机构 代理人
主权项
地址