| 发明名称 |
METHOD FOR PREPARING LACOSAMIDE |
| 摘要 |
The present invention provides a novel method for preparing lacosamide with high chiral purity from D-serine. The method of the present invention can obtain lacosamide with high chiral purity in a high yield through a simple and environmentally-friendly process and thus can be easily applied to mass production. |
| 申请公布号 |
US2016332958(A1) |
申请公布日期 |
2016.11.17 |
| 申请号 |
US201415034536 |
申请日期 |
2014.10.27 |
| 申请人 |
ST PHARM CO., LTD. |
发明人 |
LIM Geun Jho;CHANG Sun Ki;KIM Jae Hun;PARK Jong Moon |
| 分类号 |
C07C231/12;B01J23/04 |
主分类号 |
C07C231/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for preparing lacosamide represented by Formula 1, the method comprising:
preparing a compound represented by Formula 3 by reacting a compound represented by Formula 2 with a methylating agent in the presence of an inorganic lithium compound: wherein in Formula 1, Bn represents a benzyl group. |
| 地址 |
Gyeonggi-do KR |
