Method for producing scyllo-inositol

摘要

The disclosure provides a method of producing a scyllo-inositol or a new scyllo-inositol derivative in a one-step process, from ubiquitous and inexpensive raw materials. Also provided is a scyllo-inositol derivative bonded to saccharides such as glucose and similar.

主权项

1. A method for producing scyllo-inositol and a scyllo-inositol derivative comprising:
preparing a transformed microorganism by transfecting a host microorganism with expression cassettes comprising an inositol-1-phosphoric acid synthase gene, inositol monophosphatase gene, myo-inositol dehydrogenase gene, and iolW gene to overexpress said genes in the transformed microorganism, wherein the host microorganism is Escherichia coli; and contacting the transformed microorganism with glucose or disaccharides or polysaccharides having glucose units under conditions suited to the growth and/or maintenance of the transformed microorganism.