| 发明名称 |
Amide-substituted heterocyclic compounds useful as modulators of IL-12, IL-23 and/or IFNα responses |
| 摘要 |
Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNa, by acting on Tyk-2 to cause signal transduction inhibition.; |
| 申请公布号 |
US9505748(B2) |
申请公布日期 |
2016.11.29 |
| 申请号 |
US201314441183 |
申请日期 |
2013.11.07 |
| 申请人 |
Bristol-Myers Squibb Company |
发明人 |
Moslin Ryan M.;Weinstein David S.;Wrobleski Stephen T.;Tokarski John S.;Lin Shuqun;Spergel Steven H.;Zhang Yanlei |
| 分类号 |
C07D417/12;C07D417/14;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D237/24;C07D413/12;C07D413/14 |
主分类号 |
C07D417/12 |
| 代理机构 |
|
代理人 |
Korsen Elliott |
| 主权项 |
1. A compound which isor a stereoisomer or pharmaceutically-acceptable salt thereof. |
| 地址 |
Princeton NJ US |
