| 发明名称 | Hydroxamic acids and uses thereof | ||
| 摘要 | Compounds of formula I are provided:; R1 is an alkoxy or O(CH2)pX, p is an integer from 2 to 3 and X is OH, NH2, or CO2H, m is an integer from 0 to 5, n is an integer from 0 to 5, each R2 is independently selected from hydrogen, alkenyl, hydroxyalkyl, alkoxymethyl, heterocyclyl, hetereocyclylmethyl, amino, amido, hydroxamido, any of which may be optionally substituted with one or more of acyl, alkyl, alkoxy, hydroxyalkyl, or halogen, each R3 is independently selected from hydrogen, halogen, alkyl, alkenyl, carboxy, hydroxymethyl, amido, and at least one of R2 and R3 is not hydrogen. | ||
| 申请公布号 | US9505710(B2) | 申请公布日期 | 2016.11.29 |
| 申请号 | US201615099438 | 申请日期 | 2016.04.14 |
| 申请人 | HAWAII BIOTECH, INC. | 发明人 | Johnson Alan Thomas;Kim Seong Jin;O'Malley Sean;Jackson Henry Lee |
| 分类号 | C07C259/06;C07D213/56;C07D295/16;C07C259/10;C07D207/337;C07D239/26;C07D239/42;C07D231/12;C07D295/185;C07D295/155;C07D233/64;C07D303/46;C07D211/34 | 主分类号 | C07C259/06 |
| 代理机构 | Pillsbury Winthrop Shaw Pittman | 代理人 | Pillsbury Winthrop Shaw Pittman |
| 主权项 | 1. A compound of formula I: wherein R1 is an alkoxy or O(CH2)pX; wherein p is an integer from 2 to 3 and X is OH, NH2, or CO2H; m is an integer from 0 to 5; n is an integer from 0 to 5; each R2 is independently selected from the group consisting of halogen, hydrogen, alkenyl, hydroxyalkyl, alkoxymethyl, heterocyclyl, hetereocyclylmethyl, amino, amido, hydroxamido, any of which may be optionally substituted with one or more of acyl, alkyl, alkoxy, hydroxyalkyl, or halogen; each R3 is independently selected from the group consisting of hydrogen, halogen, alkyl, alkenyl, carboxy, hydroxymethyl, amido; and wherein at least one of R2 and R3 is not hydrogen. | ||
| 地址 | Honolulu HI US | ||