| 发明名称 |
MACROAGGREGATED ALBUMIN-POLYETHYLENEIMINE (MAA-PEI) LUNG-TARGETED DELIVERY OF RESPIRATORY SYNCYTIAL VIRUS DNA VACCINES |
| 摘要 |
<p>The present invention provides a composition comprising: 1) macroaggregated albumin, 2) a nucleic acid comprising a nucleotide sequence encoding an RSV protein, and 3) polyethylamine (PEI), wherein the MAA, PEI and nucleic acid form a complex. Also provided by the present invention is a method of preventing respiratory syncytial virus (RSV) infection in a subject comprising administering to the subject an amount of a composition of this invention.</p> |
| 申请公布号 |
CA2388456(A1) |
申请公布日期 |
2003.11.30 |
| 申请号 |
CA20022388456 |
申请日期 |
2002.05.31 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CO NTROL AND PREVENTION |
发明人 |
TRIPP, RALPH |
| 分类号 |
A61K31/7084;A61K31/785;A61K38/38;A61K39/155;A61K47/48;C07K16/10;C12N15/87;(IPC1-7):C12N15/34;C12N15/12 |
主分类号 |
A61K31/7084 |
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