HYBRID WITH INTERFERON-(ALPHA) AND AN IMMUNOGLOBULIN FC LINKED THROUGH A NON-IMMUNOGENIC PEPTIDE

摘要

DISCLOSED IS A HYBRID RECOMBINANT PROTEIN CONSISTING OF HUMAN INTERFERON, PREFERABLY INTERFERON-A (IFNA), AND HUMAN IMMUNOGLOBULIN FC FRAGMENT, PREFERABLY G4 CHAIN, JOINED BY A PEPTIDE LINKER COMPRISING A T CELL INERT SEQUENCE, FOR EXAMPLE, THE SEQUENCE GLY GLY SER GLY GLY SER GLY GLY GLY GLY SER GLY GLY GLY GLY SER.