摘要 |
PROBLEM TO BE SOLVED: To provide a new compound effective for prevention and therapy of various diseases caused by aberrant growth of vascularization. SOLUTION: The compound represented by general formula (I), or its salt or hydrate äwherein, A<SP>g</SP>is a (substituted) 5- to 14-membered heterocyclic group or the like; X<SP>g</SP>is O, S or the like; Y<SP>g</SP>is a (substituted) 6-14C aryl, a 5- to 14-membered heterocyclic group or the like; and T<SP>g1</SP>is a group represented by formula 1, or the like, [wherein, E<SP>g</SP>is a single bond or N(R<SP>g2</SP>) or the like; R<SP>g1</SP>and R<SP>g2</SP>are each independently H or a (substituted) 1-6C alkyl or the like; and Z<SP>g</SP>is a 1-8C alkyl, a 3-8C alicyclic hydrocarbon, a 6-14C aryl or the like]} is provided. COPYRIGHT: (C)2006,JPO&NCIPI |