| 摘要 |
<p>1286761 Vitamin-active preparations UPJOHN CO 11 Feb 1970 [17 March 1969] 6597/70 Heading A5B [Also in Division C2] Pharmaceutical or veterinary preparations comprise as active ingredient having Vitamin D-like activity (i.e. promoting the intestinal reabsorption of calcium and the mobilization of calcium from bone) a compound of the formula: (wherein R 1 and R 2 are each H, alkyl or cycloalkyl of at most 8 carbon atoms, or phenyl; R 3 and R 5 are each H or acyl derived from a hydrocarbon carboxylic acid of less than 12 carbon atoms; n is 2, 3 or 4; and x is 0, ¢, 1, 1¢ or 2 provided that when R 1 and R 2 are CH 3 , n is 3 and R 3 and R 5 are H, then x is not zero) and a suitable carrier. They may also contain a corticosteroid and in this instance the compound having Vitamin D-like activity may be the compound excluded in the above definition viz 25-hydroxycholecalciferol. Specified corticosteroids include hydrocortisone, cortisone, prednisone and prednisolone and their substitution products and esters, including acetonides of 16α, 17α-diols.</p> |
