摘要 |
Title compd. (I;Z = H or cation; n = 0-1; R2 = C1-8 alkyl, C3-4 alkenyl; R3 = Furyl, thienyl, pyridyl), useful as antiallergics, was prepd. by the hydrolysis of II(R1 = C2-5 alkanoyloxy, C1-20 alkyl). Thus, 2.4 g trans 6-carbomethoxy-3-propyl-2-[2-(2'-methyl-phenyl)-cyclopropyl -chromone and 95 % ethanol contg. 1 % KOH were reacted at refluxing temp to give 1.8 g trans 6-carboxy-3-propyl-2[2-(2'-methyl-phenyl)-cyclopropyl -chromone(m.p. 206-207≦̸C).
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