由苯骈咪唑异构物移除磺醯基之方法,申请号TW07210758-传众专利搜索

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发明名称	由苯骈咪唑异构物移除磺醯基之方法
摘要
申请公布号	TW057918	申请公布日期	1984.04.16
申请号	TW07210758	申请日期	1983.03.14
申请人	礼来大药厂	发明人	杰米贺华威尔;蒂那玛利摩威克
分类号	A61K31/41;C07D235/20	主分类号	A61K31/41
代理机构		代理人	陈长文台北巿敦化北路二○一号七楼
主权项	1﹒制备如下式之2一胺基一5(6)一苯骈咪唑之方法:其中R3为R4一C一;其中R4为C1一C2烷基或苯基;Z是氧 ,C1一C2次烷基或C1一C2烷氧基亚胺基。M则为金属阳离子或水合氢离子 ;本方法包括使式Ⅱ之1一磺醯基一2一胺基一5(6)一经取代一苯骈咪唑其中 R3之定义同前R为C1一C3烷基,与硷金属氢氧化物如氢氧化钠在惰性水溶性有机溶剂系统如丙酮中于温度约20℃至 100℃起反应。 2﹒根据上述请求专利部份第1项之方法,其中温度为回流温度。
地址	美国

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