| 发明名称 |
Therapeutic Polymeric Nanoparticles Comprising Vinca Alkaloids and Methods of Making and Using Same |
| 摘要 |
The present disclosure generally relates to therapeutic nanoparticles. Exemplary nanoparticles disclosed herein may include about 1 to about 20 weight percent of a vinca alkaloid; and about 50 to about 99 weight percent biocompatible polymer. |
| 申请公布号 |
US2016338963(A1) |
申请公布日期 |
2016.11.24 |
| 申请号 |
US201615137682 |
申请日期 |
2016.04.25 |
| 申请人 |
BIND Therapeutics, Inc. |
发明人 |
Zale Stephen E.;Troiano Greg;Ali Mir M.;Hrkach Jeff;Wright James |
| 分类号 |
A61K9/16;A61K47/26;A61K31/475 |
主分类号 |
A61K9/16 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A therapeutic nanoparticle comprising:
about 1 to about 20 weight percent of a vinca alkaloid; and about 50 to about 99 weight percent biocompatible polymer, wherein the biocompatible polymer is selected from the group consisting of
a) a diblock poly(lactic) acid-poly(ethylene)glycol copolymer,b) a diblock poly(lactic)-co-(glycolic) acid-poly(ethylene)glycol copolymer,c) a combination of a) and a poly (lactic) acid homopolymer or poly(lactic)-co-(glycolic) acid; andd) a combination of b) and a poly (lactic) acid homopolymer or poly(lactic)-co-(glycolic) acid. |
| 地址 |
Cambridge MA US |
