| 摘要 |
NEW MATERIAL:The macrolide antibiotic substance P-59B1 of formula having the following physico-chemical properties. Appearance, neutral oily substance having yellow color; molecular formula, C21H32O6; solubility, soluble in lower alcohol, ethyl acetate, acetone, chloroform and benzene, hardly soluble in water; color reactions, positive to sulfuric acid reaction and iodine reaction, negative to ninhydrin and Lemieux reactions; stability, unstable in acidic and alkaline state. USE:An antibacterial agent. PREPARATION:A microbial strain such as Micromonospora chalcea 980-MCI (FERM-P No.7046) is cultured preferably under aerobic condition at 26-32 deg.C for 2-7days. |
