发明名称 |
INTERLEUKIN-2 PRODUCTION USING CLONED GENES FOR INTERLEUKIN-2 AND YEAST ALPHA-FACTOR |
摘要 |
Methods and compositions for efficient production of human interleukin-2. A synthetic interleukin-2 gene is joined to yeast alpha-factor secretory leader and processing signals to provide for expression and secretion of mature gene product in yeast. Enhanced yields of the product may be recovered from the nutrient medium. |
申请公布号 |
WO8502200(A1) |
申请公布日期 |
1985.05.23 |
申请号 |
WO1984US01853 |
申请日期 |
1984.11.09 |
申请人 |
CHIRON CORPORATION |
发明人 |
BARR, PHILIP, J.;MERRYWEATHER, JAMES, P. |
分类号 |
C12N15/00;C07K14/55;C12N15/09;C12N15/81;C12P21/00;C12R1/65;(IPC1-7):C12P21/00;C07H21/04;C12P21/02 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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