发明名称 |
INSERTABLE VARIABLE FRAGMENTS OF ANTIBODIES AND MODIFIED A1-A2 DOMAINS OF NKG2D LIGANDS |
摘要 |
This application relates generally to the production of polypeptides having specific antigen-binding properties of Fv domains, for example, insertable variable fragments of antibodies, and modified α1-α2 domains of NKG2D ligands. This application further relates to modified α1-α2 domains of NKG2D ligands attached to polypeptides, in some embodiments antibodies or fragments of antibodies. This application further relates to antigen-binding peptides derived from light and heavy chain antibody variable domains, which contain two linker regions and a split variable domain. |
申请公布号 |
US2016304578(A1) |
申请公布日期 |
2016.10.20 |
申请号 |
US201615192400 |
申请日期 |
2016.06.24 |
申请人 |
AvidBiotics Corp. |
发明人 |
LANDGRAF Kyle;STEIGER Daniel P.;WILLIAMS Steven R.;MARTIN, JR. David W.;GEBHART Dana;BARON Tarah |
分类号 |
C07K14/705;C07K16/32;C07K16/28 |
主分类号 |
C07K14/705 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
South San Francisco CA US |