发明名称 Tetrahydrocarbazole derivatives and pharmaceutical compositions
摘要 Tetrahydrocarbazole derivatives of the general formula I <IMAGE> I in which Thc is a 1,2,3,4-tetrahydro-3-carbazolyl radical which can be substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO2-alkyl, OH, F, Cl, Br, CF3 and/or CN or by a methylenedioxy group, the two radicals Y are each H or together are a C-C bond, one radical Z is Ar and the other radical Z is H, A is -CH2- or -CH2CH2- and Ar is a phenyl group which is unsubstituted or substituted once or twice by alkyl, O-alkyl, S-alkyl, SO-alkyl, SO2-alkyl, OH, F, Cl, Br, CF3 and/or CN or by a methylenedioxy group, or is a 2- or 3-thienyl radical, and in which the alkyl groups each have 1-4 C atoms, and their physiologically acceptable acid addition salts have effects on the central nervous system.
申请公布号 US4698351(A) 申请公布日期 1987.10.06
申请号 US19860899453 申请日期 1986.08.22
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 HAUSBERG, HANS-HEINRICH;BOETTCH, HENNING;GOTTSCHLICH, RUDOLF;SEYFRIED, CHRISTOPH;MINCK, KLAUS-OTTO
分类号 C07D401/06;C07D405/14;C07D409/14;C07D491/04;C07D491/056;(IPC1-7):A61K31/44 主分类号 C07D401/06
代理机构 代理人
主权项
地址