| 发明名称 |
PHARMACEUTICAL COMPOSITIONS COMPRISING AN AROMATSE INHIBITORS |
| 摘要 |
The present invention relates to low-dose pharmaceutical compositions comprising the aromatase inhibitor 4,4′-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, as the active ingredient in a suitable carrier. The present invention also relates to a process for their preparation and to their use as medicaments. |
| 申请公布号 |
US2016346257(A1) |
申请公布日期 |
2016.12.01 |
| 申请号 |
US201615167867 |
申请日期 |
2016.05.27 |
| 申请人 |
MEREO BIOPHARMA 2 LIMITED |
发明人 |
TAYLOR Ann;KLICKSTEIN Lloyd B.;THAKUR Jeewan |
| 分类号 |
A61K31/4196;A61K9/48 |
主分类号 |
A61K31/4196 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A low-dose pharmaceutical composition, comprising a blended mixture comprising
(a) a therapeutically effective amount of 4,4′-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile; (b) one or more filler; (c) one or more disintegrant; (d) one or more lubricant, and (e) one or more glidant. |
| 地址 |
London GB |
