Cephalosporin compounds, process for their preparation and their pharmaceutical compositions.

摘要

Cephalosporin compounds having as a 3-substituent the group: <CHEM> wherein Y represents a bond, optionally substituted alkylene or -CH2CH2NHCO-, P is a benzene ring substituted by groups W and Z ortho with respect to one another wherein W is hydroxy or an in vivo hydrolysable ester thereof, Z is hydroxy, an in vivo hydrolysable ester thereof, carboxy, sulpho, hydroxymethyl, -NHSO2CH3 or NHCONH2, Q is a mono- or bicyclic ring system substituted by R<7> wheein R<7> is hydrogen or a range of groups and ring Q is optionally further substituted; are described as antibacterial agents. Processes for their preparation and their methods of use are described.