Tissue ligation devices and tensioning devices therefor

摘要

Described here are closure devices and methods for ligating tissue, such as the left atrial appendage, and tensioning devices and mechanism for actuating these devices. The tensioning mechanisms and devices may allow a user to apply one or more predetermined forces to a suture or other portion of the closure devices. The closure devices may comprise a suture loop releasably attached to a snare loop assembly, and a tensioning mechanism or device may be configured to tighten the suture loop and/or release the suture loop from the snare loop assembly.

主权项

1. A method of closing a left atrial appendage comprising:
introducing a closure device into a body, wherein the closure device comprises a snare loop assembly having an open configuration and a closed configuration and comprising a suture loop releasably coupled to the snare loop assembly; advancing the snare loop assembly to ensnare the left atrial appendage; closing the snare loop assembly around the left atrial appendage; applying a tension to the suture loop to release the suture loop from the snare loop assembly; after releasing the suture loop, applying a first predetermined tension to the suture loop to tighten the suture loop around the left atrial appendage, wherein the first predetermined tension is at least 10 pounds and is applied using a separate tensioning device; and applying a second predetermined tension to the suture loop using the separate tensioning device to re-tighten the suture loop around the left atrial appendage.