| 摘要 |
The compounds of the formula …<IMAGE>… in which R<1> denotes hydrogen, lower alkyl which is optionally substituted by hydroxyl, lower alkoxy, cyano, halogen, lower alkoxycarbonyl, aminocarbonyl, substituted benzoyl or substituted alpha -hydroxybenzyl, lower alkenyl, cycloalkyl, cycloalkyl-lower alkyl, heteroaryl-lower alkyl or aryl-lower alkyl which is optionally substituted by hydroxyl, lower alkoxy, lower alkyl or halogen and R<2> denotes hydrogen or lower alkanoyl,… in the form of the racemates and the optical antipodes and pharmaceutically utilisable acid addition salts thereof are active as selective presynaptic dopamine receptor agonists and are therefore suitable for the control or prevention of diseases of the central nervous system, in particular for the control or prevention of psychotic disorders, such as chronic schizophrenia. They can be prepared by various processes which are known per se. |
