Hydrophilic laminated porous membranes and methods of preparing same.

摘要

Laminated porous membranes useful in chromatographic assay devices include nitrocellulose or polyvinylidene difluoride (PVDF) membranes laminated to supports. Despite lamination, the membranes remain wettable and the activity of biologically reactive reagents is not impaired, even when organic solvent based adhesives are used, due to the incorporation of an agent of the formula: R1N(CH3)+_3 . SO-_4R2 in a concentration range of from about 0.1% to about 0.2% (w/w) for nitrocellulose, and from about 2% to about 10% (w/w) for PVDF membranes. R1 and R2 are nonpolar, preferably alkyl moieties.