Trans-platinum compounds with anti-tumor activity, process for their preparation and compositions containing them.

摘要

Trans-Pt(IV) compounds of general formula [PtX2Y2L<1>L<2>)] where X is halogen, Y is halogen, hydroxyl or carboxylate and each L is an amine ligand, providing L<1> and L<2> are not both NH3 are surprisingly active against cancer cells, in contrast to expectations that all trans-Pt compounds are inactive.