| 发明名称 |
INHIBITORS OF FARNESYL PROTEIN TRANSFERASE |
| 摘要 |
134/MRD86 18628 TITLE OF THE INVENTION INHIBITORS OF FARNESYL PROTEIN TRANSFERASE The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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| 申请公布号 |
CA2085282(A1) |
申请公布日期 |
1993.06.17 |
| 申请号 |
CA19922085282 |
申请日期 |
1992.12.14 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
SINGH, SHEO B. |
| 分类号 |
A61K31/19;A61K31/23;A61P35/00;A61P43/00;C07C57/13;C07C57/155;C07C69/347;C07C69/593;C12N9/99;(IPC1-7):C07C57/13;A61K31/225;C07C69/65 |
主分类号 |
A61K31/19 |
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