摘要 |
An interleukin-1 inhibiting agent which comprises as an active ingredient a benzoheterocyclic compound of formula (I) or (II) wherein R<1> and R<2> are each a lower alkyl group and X<1> is a halogen atom, R<3> is a lower alkyl group, R<4> is a hydroxy group, and X<2> is a halogen atom, or a pharmaceutically acceptable salt, and a method for prophylaxis and treatment of various diseases induced by acceleration of IL-1 secretion by administering said interleukin-1 inhibiting agent. |
申请人 |
OTSUKA PHARMACEUTICAL COMPANY, LIMITED;ADACHI, MASAKAZU;TAMAOKA, HISASHI;ONO, YUKIHISA |
发明人 |
ADACHI, MASAKAZU;TAMAOKA, HISASHI;ONO, YUKIHISA |