发明名称 |
Method for Differentiating Pluripotent Stem Cell Induced From Mesenchymal Stem Cell into Hepatocyte |
摘要 |
The present invention relates to a medium composition containing an Ecklonia cava extract for dedifferentiation an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced pluripotent stem cell produced by using the medium composition into hepatocytes. When using the medium composition according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into hepatocytes. |
申请公布号 |
US2016272936(A1) |
申请公布日期 |
2016.09.22 |
申请号 |
US201315033405 |
申请日期 |
2013.11.05 |
申请人 |
BBHC CO., LTD. |
发明人 |
LEE Sang Yeon;JUNG Won Ju;KIM Ho Bin;OH Min Sun;LEE Kye Ho |
分类号 |
C12N5/071;A61K35/407 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
1. A method for differentiating mesenchymal stem cells into hepatocytes, comprising the steps of:
(a) adding an Ecklonia cava extract to a cell culture medium; (b) dedifferentiating mesenchymal stem cells into induced pluripotent stem cells in the medium; and (c) differentiating the induced pluripotent stem cells into hepatocytes. |
地址 |
Yongsan-gu Seoul KR |