Labelling color, method of preparing the same and method for detecting methamphetamine with the color

摘要

A labelling color of pentamethine, its intermediate and a method for preparing and using the same to detect methamphetamine with high sensitivity. The invention is exemplified by pentamethine of the following Formula (1): Formula (1) wherein R1, R2, R3 and R4 each are a C1-6alkyl group, and X is an anion. A method for using the labelling color to detect methamphetamine. The method comprises preparing a solution of the labelling color and methamphetamine-antibody in a buffer, measuring its fluorescent intensity at 660 nm in a 600 nm excited state, adding methamphetamine in a buffer to the solution, measuring its fluorescent intensity similarly, and examining the change in fluorescent intensity between both solutions.