发明名称 Androgenic directed compositions
摘要 Substituted phenylthiohydantoins are provided for use in detecting the presence of tumor cells having androgenic receptors and providing for cytostatic and cytotoxic activity toward such cells. The subject compounds provide for vehicles for specific targeting to the androgenic receptor containing cells of cytostatic and/or cytotoxic agents, heavy or light radioactive or radioopaque atoms, and the like for detection and treatment of cancer cells involving androgenic receptors or blocking androgenic receptors.
申请公布号 US5656651(A) 申请公布日期 1997.08.12
申请号 US19950491130 申请日期 1995.06.16
申请人 BIOPHYSICA INC. 发明人 SOVAK, MILOS;BRESSI, JEROME C.;DOUGLASS, III, JAMES GORDON;CAMPION, BRIAN;WRASIDLO, WOLFGANG
分类号 A61K31/415;A61K31/4166;A61K31/555;A61K38/00;A61K49/04;A61K51/04;A61P35/00;C07D233/72;C07D233/74;C07D233/84;C07D233/86;C07D233/88;C07D405/06;C07F7/22;C07K5/062;(IPC1-7):A61K31/415;C07D405/04 主分类号 A61K31/415
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