The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
申请公布号
WO9736886(A1)
申请公布日期
1997.10.09
申请号
WO1997US05384
申请日期
1997.04.01
申请人
MERCK & CO., INC.;ANTHONY, NEVILLE, J.;GOMEZ, ROBERT, P.;SOLINSKY, KELLY, M.
发明人
ANTHONY, NEVILLE, J.;GOMEZ, ROBERT, P.;SOLINSKY, KELLY, M.
