Use of theophylline derivatives for the treatment and prophylaxis of states of shock, novel xanthine compounds and processes for their preparation.

摘要

Use of at least one compound of formula (I), or their salts or stereoisomeric forms for preparation of a medicament for treatment and/or prophylaxis of shock disorders is claimed: R1 = 1-5C alkyl, 1-2C alkoxy(1-3C)alkyl, or phenyl or phenyl(1-2C)alkyl (both optionally ring substituted by 1-2 halo); A = a 1-4C alkylene bridge; R2 = 1-5C alkyl, 3-6C cycloalkyl, 4-8C cycloalkyl-alkyl, phenyl or phenyl(1-2C)alkyl. Compounds (I), and their salts and stereoisomeric forms are new with the exception of those compounds in which (a) R2 = n-propyl, R1 = ethyl and A = a (m)ethylene bridge and (b) R2 = n-propyl, R1 = propyl and A = a methylene bridge.