| 摘要 |
PROBLEM TO BE SOLVED: To obtain a preparation for external use for skin, having an excellent wrinkle-improving effect. SOLUTION: This preparation is characterized by incorporating (A) 1 kind of >=2 kinds selected from agaric acid and its salts, and lipoic acid and its salts, and (B) 1 kind or >=2 kinds selected from triterpenes, sphingoid-based compounds, slindac, an oxidized type CoA and its salts, and organic silicon compounds such as a lower alkylsilanol and a peptide derivative of the lower alkylsilanol.
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