发明名称 |
UNILAMELLAR LIPOSOMAL PREPARATIONS WITH HIGH ACTIVE SUBSTANCE CONTENT |
摘要 |
<p>A liposomal vesicular preparation with good encapsulation efficiency for active ingredients, based on homogeneous unilamellar liposomal vesicular lipids, has a substantially tightly packed vesicular structure and forms carriers of active ingredients. At least 20% by weight relative to the total weight of the liposomal vesicular preparation of the active ingredient (drug substances, vaccines, diagnostics, vectors) are present in encapsulated form inside the homogeneous unilamellar liposomal vesicular lipids. The liposomal vesicular preparation is a semi-solid liposomal vesicular lipid gel. The membrane forming amphiphiles can be members of from the group consisting of lipids, phospholipids and synthetic amphiphiles.</p> |
申请公布号 |
EP0776194(B1) |
申请公布日期 |
2003.05.02 |
申请号 |
EP19950944702 |
申请日期 |
1995.08.18 |
申请人 |
MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN;BRANDL, MARTIN, PROF. DR. |
发明人 |
BRANDL, MARTIN;BACHMANN, DIETER;RESZKA, REGINE;DRECHSLER, MARKUS |
分类号 |
A61K9/127;A61K9/133;(IPC1-7):A61K9/133;A61K31/28 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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