发明名称 THERAPEUTIC COMPOSITIONS (U)
摘要 FIELD: medicine, therapy. ^ SUBSTANCE: invention relates to applying (R)-3-hydroxybutyrate cyclic ester of the formula (1) given in the description of invention. This compound is used for treatment of morbid states mediated by free radicals, toxic agents, such as peptides and proteins and genetic defects that are harmful for metabolism in cell, resistance to insulin or other defects in metabolism of glucose or states causing defect, ischemia, head traumas and/or for enhancing effectiveness in cell activity. Compound of the formula (1) elicits the enhanced effectiveness in elevating the level of (R)-3-hydroxybutyric acid, maintenance of its enhanced level for some hours, possibility of administration without counter-ion and simple method for preparing. ^ EFFECT: valuable medicinal properties of compositions. ^ 16 cl, 1 dwg, 6 ex
申请公布号 RU2242227(C2) 申请公布日期 2004.12.20
申请号 RU20010110097 申请日期 1999.09.15
申请人 发明人 VICH RICHARD L.
分类号 A61K31/357;A61K31/365;A61P3/10;A61P9/10;A61P21/04;A61P25/08;A61P25/16;A61P25/28;A61P43/00;C07D323/00 主分类号 A61K31/357
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